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Smoke exposure and atopic dermatitis in offspring

A new study has looked into the effect of prenatal smoke exposure on the development of atopic dermatitis (AD).
The study included 264 mothers and their newborns. Maternal blood and cord cotinine levels were used as proxy measures of smoke exposure, and at 2 years of age information on AD and environmental exposures was collected. 150 mothers and their children completed the follow-up study.  In 38 (25.3%) cases the children developed AD. Only 2 of the 150 mothers (1.3%) smoked during the pregnancy and 38 (25.3%) reported having environmental tobacco smoke exposure.
 
Konklusion
The study indicates that the risk of AD increases dose-dependently with the levels of cotinine in the maternal blood and the cord (p for trend = 0.01). Avoidance of smoke exposure in the pregnancy is thus one factor which can decrease AD development.

Source: (Wang, I.-J. et al. Ped Allergy Immunol 2008, doi 10.1111/j.1399-3038.2008.00759.x).