News: Lymphoma risk following calcineurine inhibitors and tropicalThe use of calcineurine inhibitors is thought to be a risk factor
in the developing of lymphoma. However, new research found no
association between lymphoma and treatment with calcineurine.
A database describes 300 cases of lymphoma. The database consists
of 300.00 patients with atopic eczema who are treated with prednisolon,
local steroids group 1-4 and calcineurin inhibitors.
In the calculation of the odds ratios of the different treatments
there was found no significant risk in the incidence of lymphoma in the
group who was treated with calcineurin inhibitors compared with the all
the remaining treatments.
The study found that the risk of lymphoma was primarily related to
the severity of atopic eczema where a systematic treatment with
prednisolon may be required.
Reference: F.M. et al. J Invest Dermatol 2007, 127 (4): (808-816)
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